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Best Vitamin C Serum in United States: Dermatologist recommended

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Best Vitamin C Serum in United States: Dermatologist recommended

Loking for dermatologist recommended Vitamin C serum in United States?

Vitamin C serum is definitely worth adding to skin care regime in all skin type because it has something in store for every skin problem. Of the various forms of Vitamin C available in the market, L-ascorbic acid is most potent, but least stable. Therefore, a researched formulation that can keep the goodness of Ascorbic acid is the one that you should look for.

Dermatocare team researched the ingredients list of popular Vitamin C serum available in the United States before compiling this article. We found so much variety to tackle each skin concern. Scroll further to know the best Vitamin C serum in United States  for ageing skin, pigmentation, oily skin and acne-prone skin.

Best Vitamin C serum for Ageing skin

Vitamin C serum with combination of ascorbic acid with Vitamin E and ferulic acid is 8 fold more potent than ascorbic acid alone for photo-aged skin that dark spots, roughness, laxity. The unique thing about this combination is its ability to act in both water-soluble and lipid-soluble compartment of skin cells. Vitamin C acts in water compartment and Vitamin E acts in the lipid compartment of the skin cell.

This set of Vitamin C serum might irritate sensitive skin, therefore cautious use is recommended.


SkinCeuticals Vitamin C serum:


  • Has trio of 15% Ascorbic acid, Vitamin E and Ferulic acid
  • Has water based patented formula that ensure absorption and non-sticky feel of the product
  • Recommended by dermatologist


  • It is most expensive option in this category
  • It is packed in a dropper bottle that can expose product to air affecting the stability of precious L-ascorbic acid.

AVAILABILITY: Check Prize on


Cosmetic skin solutions


  • Has 15% L-Ascorbic acid and  Vitamin E.
  • In addition, it contains Asiatic Acid, a potent anti-oxidant
  • Has Hyaluronic acid that can help in hydrating your skin and add a plump to your skin.
  • Has patented technology that ensure the maximum penetration.


  • It is packed in a dropper bottle that can expose product to air affecting the stability of precious L-Ascorbic acid.

AVAILABILITY: Check price on

La Roche Posay Redermic C serum

La Roche Posay Redermic C serum has 3 potent and scientifically proven anti-ageing ingredients, namely:

  • L Ascorbic acid- The concentration of L-Ascorbic acid is low. It is 5%, compared to recommended 10-15 %. This is advantageous for sensitive skin. Also, combined with retinol and fragmented hyaluronic acid, it gives an edge.
  • Fragmented Hyaluronic acid: Hyaluronic acid molecule cannot seep into dermis because of big size. This is works as moisturiser only. La Roche Posay Redermic C serum has segmented hyaluronic acid that can seep into dermis. Company claims, this serum visible plumps up the skin.
  • Retinol: This is star ingredient. Retinol is proven ant-ageing ingredient. It reduces fine lines and wrinkles.

La Roche Posay Redermic C serum can be tried by sensitive skin types. It should be applied at night only.

Available at

Timeless Skin Care 20% Vitamin C + E Ferulic Acid Serum


  • Has trio of ascorbic acid with Vitamin E and ferulic acid
  • Has 20 % L ascorbic acid that imparts extra benefit, but might not suit sensitive or aged skin
  • Most suitable for stubborn skin types, that do not get irriatated easily.
  • A good choice for males.
  • Come in an air-tight pump packing that does not exposes the product to air or sunlight.


  • Might not suit senstive skin, cautious use is recommended only after skin gets calm.


Flavo-C Ultraglican by ISDIN


  • Vitamin C is the form L-ascorbic acid
  • UltraGlycan is combination of proteoglycans and pre-proteoglycans, which support firmness and elasticity in the skin and provide radiance.
  • Hyaluronic restore moisturization level of your skin
  • It is best suited for dry and sagging because it can provide hydartion and firmness along with skin repair.
  • Unlike other products in this category, it is can be tried on sensitive skin.
  • Comes in ampoule that ensure the stabilty of Ascorbic acid.
  • Trusted brand


  • Percentage of ascorbic acid not mentioned
  • Ampoule packing diificult to open, though product comes with protective cap to break the ampoule.


Best Vitamin C Serum for pigmentation

Vitamin C reduces dark spots by skin lightening action and prevents the formation new dark spots or patches by reversing the oxidative damage caused by UV rays. Addition of agents like niacinamide, Hydroxyresorcinol and glycolic acid further enhances the skin lightening action of product.

Procelain Skin Whitening Serum


  • Has Tetrahexyldecyl Ascorbate form of Vitamin C, which is stable but not most potent form. It is not primarily a Vitmin C serum, but a skin lighteing serum with Vitamin C.
  • Has 4 potent and effective skin lightening agents- Glycoloc aicd, Hydroquinone, Kojic acid and Licorice extarct.
  • Hydroquinone at 2 % concentration is safe, yet very effective skin lightening agent.
  • Glycloic acid is definetly worth trying because it exfoliates, hydrates and brightens the skin.
  • Overall a good product for skin lightening in non-sensitive skin.


  • Percentage of glycolic acid, kojic acid and Vitamin C is not mentioned
  • Should not be used on sensitive skin.
  • Avoid if your skin burns, gets red, or rashes appear on using this product.
  • Sun protection in the form of regular use of suncreen is recommended with this product.

Available @

PCA SKIN C&E Advanced


  • L-ascorbic acid is pesent at higher concentration of 20% increasing it skin lightening and repairing action.
  • Vitamin E at 5% concentration has antioxidant and hydrating action.
  • Hexylresorcinol 1% is an age-fighting anti-glycation agent that brightens and promotes an even skin tone while reducing future discoloration.
  • Silymarin 1% is a powerful antioxidant derived from milk thistle that has skin-calming and brightening benefits and helps fight free radical damage.
  • Air tight packing
  • Trusted brand
  • Can help in improving skin tone, but stubborn dark spots might not get better.


  • A good Vitamin C serum, but an average skin lightening agent
  • Should be used with caution on sensitive skin.

Murad Environmental Shield Vita-C Glycolic Brightening Serum


  • Has Ascorbic acid, though percentage is not mentioned.
  • Has 3 proven skin lightenig agents-glycolic acid, glutathione, All 3 can work to reduce dark spots over a period of a month or two.
  • Has skin hydrating and soothing agents agents like yeast amino acids, trehalose, inositol, decyl glucoside, marrubium vulgare meristem cell culture
  • Comes in air-tight pump bottle
  • Formulated at pH 3.9
  • Trusted brand
  • Should be used by stubborn skin that does not get irritated by harsh products.
  • Should be used at night only.



  • Percentage of glycolic acid and ascorbic acid is not mentioned
  • Should not be used on sensitive skin.
  • Sun protection in form of regular use of suncreen is recommended with this product.


Best Vitamin C serum for preventing skin ageing

If you have hit 20’s and you are looking for a product to keep your skin going, then, it is definetly Vitamin C.


Obagi Professional C Serum



  • It comes in 3 concentration-10%, 15%, 20%
  • Sensitive skin can start with 10% concentration and slowly shift to higher percentage
  • Trusted brand
  • Tinted bottle


  • It is packed in a dropper bottle that can expose product to air affecting the stability of L-ascorbic acid.



Neutrogena Rapid Tone Repair 20% Vitamin C Brightening Serum Capsules


  • L-ascorbic acid is pesent at higher concentration of 20% increasing it skin lightening and repairing action.
  • Vitamin E acts as an anti-oxidant and emolient
  • Has red raspberry etract, whicj accoording Pula’s choice inhibits enzymes in skin that lead to signs of discolorations and loss of firmness.
  • Comes in sea weed derived bio-degradable capsule.
  • Can be tried in combination skin type.


  • Use with caution on senitive skin
  • Dimethicone base might be occlusive for oily-acne prone skin.




L ascorbic acid form of Vitamon C might not suit super sensitive skin types, however, if your skin is calm, not breaking out, irritated or burning, then you can start using 10% L-Ascorbic acid. If this does not suits you, then go compound form of Ascorbic acid listed below

CeraVe Vitamin C Serum with Hyaluronic Acid


  • Has 10 % L-Ascorbic acid
  • Has multiple hydrating agents like Sodium Hayaluronate, Xanthum gum, Ceramides
  • 3 form of Ceramide help in repairing skin barrier of your skin, along with providing deep hydration
  • One of few Vitamin C serum that can be used for dry skin types
  • Air-tight opaque packing
  • Affordable


  • Not for stubborn dark spots, or aged skin, but definetly good for prevention of ageing, skin repair and hydration.

Available at:

RoC Multi Correxion Revive + Glow Vitamin C Serum



  • Has 10 % 3-O-Ethyl-Ascorbic acid
  • Hadrating water, castor oil and glycerine based product
  • Has 4 potent anti-oxidant and anti-infalammatory ingredeints- Troxerutin, Cistus Monspeliensis Flower/Leaf/Stem Extract, Polygonum Aviculare Extract, Terminalia Ferdinandiana Fruit Extract,
  • Nonapeptide-1 is skin whtening peptide that can prevent melanin synthesis and unwanted pigmentation by preventing activation of the tyrosinase, thus allowing for a better control over skin tone.
  • Overall a good product for sensitive skin prone to pigmentation


  • It is packed in a dropper bottle that can expose product to air. However, Ethyl ascorbic acid is more stable than L-ascorbi acid.



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